Mastering Loot Collection in Resident Evil Requiem
One of the most effective strategies for gaining a significant advantage early in Resident Evil Requiem involves systematically breaking into safes and lockers scattered throughout the game world. Opening every sealed container can provide players with a crucial edge, whether they are hunting for Antique Coins to spend in the Parlor or preparing for intense monster encounters.
Understanding Safe Mechanics Across Difficulties
While the game features numerous safes across key locations like the Care Center and ARK facility, most key combinations remain fixed and do not vary between standard playthroughs. However, a critical twist occurs for players tackling the Insanity difficulty setting. On this challenging mode, the codes themselves are entirely different, though the valuable rewards inside each safe remain consistent. This guide provides a complete, detailed breakdown of all locker and safe code solutions to ensure no loot is left behind.
Care Center Locker and Safe Codes
The majority of early-game locked containers are concentrated in the Rhodes Hill Care Center, particularly within the East and West Wings. It is essential to note that these containers can only be opened while controlling the character Grace. Players must prioritize unlocking them before progressing too far in the storyline to avoid missing out.
Examination Room Safe
- Location: East Wing, first floor, positioned inside a cupboard adjacent to the examination table.
- Prize: 3 Old Coins.
- Normal/Casual Code: Right 30 → Left 10 → Right 50.
- Insanity Code: Left 50 → Right 30 → Left 90.
A helpful clue for this combination can be discovered upstairs, near the Lead Researcher's Office, aiding players in their puzzle-solving efforts.
Bar & Lounge Safe
- Location: West Wing, second floor, concealed behind the bar counter.
- Reward: 3 Antique Coins.
- Normal/Casual Code: Left 10 → Right 80 → Left 30.
- Insanity Code: Right 20 → Left 50 → Right 30.
This area is notoriously patrolled by a dangerous Screamer zombie. It is highly advisable to clear the room of threats before attempting to dial the safe to avoid interruptions.
Waiting Room Safe
Located behind the administrative desk in the Waiting Room, this safe is already open and does not require any code, offering immediate access to Antique Coins.
Basement Furnace Safe
- Location: Care Center Basement, situated near the forklift in the Furnace/Inspection area.
- Reward: Handgun Ammo and the Raccoon Roundup Map.
- Normal/Casual Code: Right 60 → Left 40 → Right 80.
- Insanity Code: Left 70 → Right 50 → Left 20.
The clue for this safe is easily missable, as it is found earlier in the game while playing as Leon. Players should exercise caution to avoid skipping relevant documents that reveal this code.
ARK Facility Locker and Safe Codes
As the narrative progresses, Grace ventures into the ARK facility, where two additional safes await unlocking, each containing essential supplies for survival.
Sterilization Chamber Safe
- Location: North side of the Sterilization Chamber.
- Reward: Med Injector, Molotov Cocktail, and Handgun Ammo.
- Normal/Casual Code: Right 10 → Left 90 → Right 20.
- Insanity Code: Left 80 → Right 50 → Left 0.
Monitor Control Room Safe
- Location: Desk at the far end of the Monitor Control Room.
- Reward: Bottle of Acid, Med Injector, and an Empty Bottle.
- Normal/Casual Code: Left 50 → Right 60 → Left 80.
- Insanity Code: Right 20 → Left 0 → Right 70.
Strategic Benefits and Completion Tips
Successfully opening all locked safes grants players the prestigious "No Safe Is Safe" accomplishment. Beyond this achievement, systematically looting these containers provides critical upgrades, ample ammunition, and valuable crafting materials, significantly enhancing gameplay efficiency.
For those aiming to achieve 100% completion, it is imperative to revisit every wing of the Care Center before advancing too far. Certain areas become permanently inaccessible later in the game, potentially locking players out of these lucrative opportunities. Diligent exploration and adherence to this guide will ensure no safe remains unopened, maximizing resource acquisition and overall success in Resident Evil Requiem.
